Wednesday, April 2, 2008

Chemotherapy

Drugs for chemotherapy generally fall into one of several categories. There are alkylating agents, anti-tumor antibiotics, Nitrosoureas, Antimetabolites, Topoisomerase Inhibitors, Mitotic Inhibitors, and Corticosteroid Hormones. This post concerns these more traditional treatments. Simply for background I will organize these drugs into their categories. This is taken from Wikipedia and provides a good overview of the current state of chemotherapy.


Double-click The terms in red for definitions

* Anti-sense oligonucleotide therapy
* AROMATASE INHIBITORS
* TGF-Beta Receptors
* Tumor Necrosis Factor-alpha Receptors
* NF-kB pathway
* Lymphotxin
* proteasome Inhibitor
* T-Cell Receptor for Antigen (TCR)
* Calcineurin
* FK506
* Cyclosporine
* Bortezomib
* monoclonal antibodies
* Infliximab
* Glucocorticoids
* SMAD proteins
* Calcium
* JAK-STAT pathways
* Receptor Tyrosine Kinases
* proto-oncogene
* PDGF
* EGF
* Trastuzumab
* Cetuximab
* RAF
* RAS
* Interferons
* IL-2
* IL-4
* Growth Hormone
* Leptin
* Prolactin
* Erythropoetin
* Thrombopoetin
* GM-CSF
* Cox Inhibitors
* Thiols
* Nitric Oxide
* MDR
* Antioxidants
* Bevacizumab
* Angiogenisis
* Oncolytic viruses
* Seneca ValleyVirus-001
* VEGF Trap (aflibercept)
* Herpes Simplex Virus NV1020
* Mullerian Inhibiting Substance
* B-Catenin
* APC tumor suppressor gene
* Wnt ligand
* Cytokine Receptors
* Signal Transduction
* v-sis

Apoptosis pathways

Apoptosis pathways

Double-click the list of technical words in red for instant definitions

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