tag:blogger.com,1999:blog-65984001605007892532011-11-27T17:10:03.950-08:00Important news in the life sciences,with a focus on cancer research. Cell signaling, apoptosis,chemotherapy mechanisms,vitamins,natural compounds.Cancer resistance mechanisms. Feeds from high quality sources of medical information are aggregated here for your convenience.writeowlnoreply@blogger.comBlogger71100tag:blogger.com,1999:blog-6598400160500789253.post-59879499764662396112008-04-02T20:53:00.000-07:002010-01-10T23:41:45.758-08:00Drugs for chemotherapy generally fall into one of several categories. There are alkylating agents, anti-tumor antibiotics, <span class="t7"> Nitrosoureas, </span><span class="t7"> Antimetabolites, </span><span class="t7"> Topoisomerase Inhibitors, </span><span class="t7"> Mitotic Inhibitors, </span><span class="t7"> and Corticosteroid Hormones. This post concerns these more traditional treatments. Simply for background I will organize these drugs into their categories. This is taken from Wikipedia and provides a good overview of the current state of chemotherapy.<br /><br /><br /></span><table id="collapsibleTable0" class="navbox collapsible autocollapse nowraplinks" style="margin: auto; background: white none repeat scroll 0% 50%; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial;"><tbody><tr><th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;"><a href="http://en.wikipedia.org/wiki/Alkylating_antineoplastic_agent" title="Alkylating antineoplastic agent">Alkylating and alkylating-like agents</a></th> <td colspan="1" style="text-align: left; width: 100%; font-size: 95%;"><i><a href="http://en.wikipedia.org/wiki/Nitrogen_mustard" title="Nitrogen mustard">Nitrogen mustards</a>:</i> (<a href="http://en.wikipedia.org/wiki/Chlorambucil" title="Chlorambucil">Chlorambucil</a>, <a href="http://en.wikipedia.org/wiki/Mechlorethamine" title="Mechlorethamine">Chlormethine</a>, <a href="http://en.wikipedia.org/wiki/Cyclophosphamide" title="Cyclophosphamide">Cyclophosphamide</a>, <a href="http://en.wikipedia.org/wiki/Ifosfamide" title="Ifosfamide">Ifosfamide</a>, <a href="http://en.wikipedia.org/wiki/Melphalan" title="Melphalan">Melphalan</a>). <i><a href="http://en.wikipedia.org/wiki/Nitrosourea" title="Nitrosourea">Nitrosoureas</a>:</i>(<a href="http://en.wikipedia.org/wiki/Bendamustine" title="Bendamustine">Bendamustine</a>, <a href="http://en.wikipedia.org/wiki/Carmustine" title="Carmustine">Carmustine</a>, <a href="http://en.wikipedia.org/wiki/Fotemustine" title="Fotemustine">Fotemustine</a>, <a href="http://en.wikipedia.org/wiki/Lomustine" title="Lomustine">Lomustine</a>, <a href="http://en.wikipedia.org/wiki/Streptozotocin" title="Streptozotocin">Streptozocin</a>). <i><a href="http://en.wikipedia.org/wiki/Platinum" title="Platinum">Platinum</a> (alkylating-like):</i> (<a href="http://en.wikipedia.org/wiki/Carboplatin" title="Carboplatin">Carboplatin</a>, <a href="http://en.wikipedia.org/wiki/Cisplatin" title="Cisplatin">Cisplatin</a>, <a href="http://en.wikipedia.org/wiki/Oxaliplatin" title="Oxaliplatin">Oxaliplatin</a>, <a href="http://en.wikipedia.org/wiki/BBR3464" title="BBR3464">BBR3464</a>, <a href="http://en.wikipedia.org/wiki/Satraplatin" title="Satraplatin">Satraplatin</a>). <a href="http://en.wikipedia.org/wiki/Busulfan" title="Busulfan">Busulfan</a>, <a href="http://en.wikipedia.org/wiki/Dacarbazine" title="Dacarbazine">Dacarbazine</a>, <a href="http://en.wikipedia.org/wiki/Procarbazine" title="Procarbazine">Procarbazine</a>, <a href="http://en.wikipedia.org/wiki/Temozolomide" title="Temozolomide">Temozolomide</a>, <a href="http://en.wikipedia.org/wiki/ThioTEPA" title="ThioTEPA">ThioTEPA</a>, <a href="http://en.wikipedia.org/wiki/Treosulfan" title="Treosulfan">Treosulfan</a>, <a href="http://en.wikipedia.org/wiki/Uracil_mustard" title="Uracil mustard">Uramustine</a></td> </tr><tr> <th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;"><a href="http://en.wikipedia.org/wiki/Antimetabolite" title="Antimetabolite">Antimetabolites</a></th> <td colspan="1" style="background: rgb(247, 247, 247) none repeat scroll 0% 50%; text-align: left; width: 100%; font-size: 95%; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial;"><i><a href="http://en.wikipedia.org/wiki/Folic_acid" title="Folic acid">Folic acid</a>:</i> (<a href="http://en.wikipedia.org/wiki/Aminopterin" title="Aminopterin">Aminopterin</a>, <a href="http://en.wikipedia.org/wiki/Methotrexate" title="Methotrexate">Methotrexate</a>, <a href="http://en.wikipedia.org/wiki/Pemetrexed" title="Pemetrexed">Pemetrexed</a>, <a href="http://en.wikipedia.org/wiki/Raltitrexed" title="Raltitrexed">Raltitrexed</a>). <i><a href="http://en.wikipedia.org/wiki/Purine" title="Purine">Purine</a>:</i>(<a href="http://en.wikipedia.org/wiki/Cladribine" title="Cladribine">Cladribine</a>, <a href="http://en.wikipedia.org/wiki/Clofarabine" title="Clofarabine">Clofarabine</a>, <a href="http://en.wikipedia.org/wiki/Fludarabine" title="Fludarabine">Fludarabine</a>, <a href="http://en.wikipedia.org/wiki/Mercaptopurine" title="Mercaptopurine">Mercaptopurine</a>, <a href="http://en.wikipedia.org/wiki/Pentostatin" title="Pentostatin">Pentostatin</a>, <a href="http://en.wikipedia.org/wiki/Tioguanine" title="Tioguanine">Thioguanine</a>). <i><a href="http://en.wikipedia.org/wiki/Pyrimidine" title="Pyrimidine">Pyrimidine</a>:</i>(<a href="http://en.wikipedia.org/wiki/Capecitabine" title="Capecitabine">Capecitabine</a>, <a href="http://en.wikipedia.org/wiki/Cytarabine" title="Cytarabine">Cytarabine</a>, <a href="http://en.wikipedia.org/wiki/Fluorouracil" title="Fluorouracil">Fluorouracil</a>, <a href="http://en.wikipedia.org/wiki/Floxuridine" title="Floxuridine">Floxuridine</a>, <a href="http://en.wikipedia.org/wiki/Gemcitabine" title="Gemcitabine">Gemcitabine</a>)</td> </tr><tr> <th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;"><a href="http://en.wikipedia.org/wiki/Spindle_poison" title="Spindle poison">Spindle poison</a>/<a href="http://en.wikipedia.org/wiki/Mitotic_inhibitor" title="Mitotic inhibitor">mitotic inhibitor</a></th> <td colspan="1" style="text-align: left; width: 100%; font-size: 95%;"><i><a href="http://en.wikipedia.org/wiki/Taxane" title="Taxane">Taxane</a>:</i> (<a href="http://en.wikipedia.org/wiki/Docetaxel" title="Docetaxel">Docetaxel</a>, <a href="http://en.wikipedia.org/wiki/Paclitaxel" title="Paclitaxel">Paclitaxel</a>). <i><a href="http://en.wikipedia.org/wiki/Vinca" title="Vinca">Vinca</a>:</i> (<a href="http://en.wikipedia.org/wiki/Vinblastine" title="Vinblastine">Vinblastine</a>, <a href="http://en.wikipedia.org/wiki/Vincristine" title="Vincristine">Vincristine</a>, <a href="http://en.wikipedia.org/wiki/Vindesine" title="Vindesine">Vindesine</a>, <a href="http://en.wikipedia.org/wiki/Vinorelbine" title="Vinorelbine">Vinorelbine</a>).</td> </tr><tr> <th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;"><strong class="selflink">Cytotoxic/antitumor antibiotics</strong></th> <td colspan="1" style="background: rgb(247, 247, 247) none repeat scroll 0% 50%; text-align: left; width: 100%; font-size: 95%; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial;"><i><a href="http://en.wikipedia.org/wiki/Anthracycline" title="Anthracycline">Anthracycline family</a>:</i> (<a href="http://en.wikipedia.org/wiki/Daunorubicin" title="Daunorubicin">Daunorubicin</a>, <a href="http://en.wikipedia.org/wiki/Doxorubicin" title="Doxorubicin">Doxorubicin</a>, <a href="http://en.wikipedia.org/wiki/Epirubicin" title="Epirubicin">Epirubicin</a>, <a href="http://en.wikipedia.org/wiki/Idarubicin" title="Idarubicin">Idarubicin</a>, <a href="http://en.wikipedia.org/wiki/Mitoxantrone" title="Mitoxantrone">Mitoxantrone</a>, <a href="http://en.wikipedia.org/wiki/Pixantrone" title="Pixantrone">Pixantrone</a>, <a href="http://en.wikipedia.org/wiki/Valrubicin" title="Valrubicin">Valrubicin</a>) - <i><a href="http://en.wikipedia.org/wiki/Streptomyces" title="Streptomyces">streptomyces</a></i> (<a href="http://en.wikipedia.org/wiki/Actinomycin" title="Actinomycin">Actinomycin</a>, <a href="http://en.wikipedia.org/wiki/Bleomycin" title="Bleomycin">Bleomycin</a>, <a href="http://en.wikipedia.org/wiki/Mitomycin" title="Mitomycin">Mitomycin</a>, <a href="http://en.wikipedia.org/wiki/Plicamycin" title="Plicamycin">Plicamycin</a>) - <a href="http://en.wikipedia.org/wiki/Hydroxyurea" title="Hydroxyurea">Hydroxyurea</a></td> </tr><tr> <th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;"><a href="http://en.wikipedia.org/wiki/Topoisomerase_inhibitor" title="Topoisomerase inhibitor">Topoisomerase inhibitors</a></th> <td colspan="1" style="text-align: left; width: 100%; font-size: 95%;"><i><a href="http://en.wikipedia.org/wiki/Camptotheca" title="Camptotheca">Camptotheca</a>:</i> (<a href="http://en.wikipedia.org/wiki/Camptothecin" title="Camptothecin">Camptothecin</a>, <a href="http://en.wikipedia.org/wiki/Topotecan" title="Topotecan">Topotecan</a>, <a href="http://en.wikipedia.org/wiki/Irinotecan" title="Irinotecan">Irinotecan</a>, <a href="http://en.wikipedia.org/wiki/Rubitecan" title="Rubitecan">Rubitecan</a>), <i><a href="http://en.wikipedia.org/wiki/American_Mayapple" class="mw-redirect" title="American Mayapple">Podophyllum</a>:</i>(<a href="http://en.wikipedia.org/wiki/Etoposide" title="Etoposide">Etoposide</a>, <a href="http://en.wikipedia.org/wiki/Teniposide" title="Teniposide">Teniposide</a>)</td> </tr><tr> <th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;"><a href="http://en.wikipedia.org/wiki/Cancer_immunotherapy" title="Cancer immunotherapy">CI</a> <a href="http://en.wikipedia.org/wiki/Monoclonal_antibodies" title="Monoclonal antibodies">monoclonal antibodies</a></th> <td colspan="1" style="background: rgb(247, 247, 247) none repeat scroll 0% 50%; text-align: left; width: 100%; font-size: 95%; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial;"><i><a href="http://en.wikipedia.org/wiki/Receptor_tyrosine_kinase" title="Receptor tyrosine kinase">Receptor tyrosine kinase</a></i> (<a href="http://en.wikipedia.org/wiki/Cetuximab" title="Cetuximab">Cetuximab</a>, <a href="http://en.wikipedia.org/wiki/Panitumumab" title="Panitumumab">Panitumumab</a>, <a href="http://en.wikipedia.org/wiki/Trastuzumab" title="Trastuzumab">Trastuzumab</a>) - <i><a href="http://en.wikipedia.org/wiki/CD20" title="CD20">CD20</a></i> (<a href="http://en.wikipedia.org/wiki/Rituximab" title="Rituximab">Rituximab</a>, <a href="http://en.wikipedia.org/wiki/Tositumomab" title="Tositumomab">Tositumomab</a>) - <i>other</i> (<a href="http://en.wikipedia.org/wiki/Alemtuzumab" title="Alemtuzumab">Alemtuzumab</a>, <a href="http://en.wikipedia.org/wiki/Bevacizumab" title="Bevacizumab">Bevacizumab</a>, <a href="http://en.wikipedia.org/wiki/Gemtuzumab" class="mw-redirect" title="Gemtuzumab">Gemtuzumab</a>)</td> </tr><tr> <th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;"><a href="http://en.wikipedia.org/wiki/Photosensitizer" title="Photosensitizer">Photosensitizers</a></th> <td colspan="1" style="text-align: left; width: 100%; font-size: 95%;"><a href="http://en.wikipedia.org/wiki/D-Aminolevulinic_acid" title="D-Aminolevulinic acid">Aminolevulinic acid</a>, <a href="http://en.wikipedia.org/wiki/Methyl_aminolevulinate" title="Methyl aminolevulinate">Methyl aminolevulinate</a>, <a href="http://en.wikipedia.org/wiki/Porfimer_sodium" title="Porfimer sodium">Porfimer sodium</a>, <a href="http://en.wikipedia.org/wiki/Verteporfin" title="Verteporfin">Verteporfin</a></td> </tr><tr> <th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;"><a href="http://en.wikipedia.org/wiki/Tyrosine_kinase" title="Tyrosine kinase">Tyrosine kinase</a> <a href="http://en.wikipedia.org/wiki/Protein_kinase_inhibitor" title="Protein kinase inhibitor">inhibitors</a></th> <td colspan="1" style="background: rgb(247, 247, 247) none repeat scroll 0% 50%; text-align: left; width: 100%; font-size: 95%; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial;"><a href="http://en.wikipedia.org/wiki/Cediranib" title="Cediranib">Cediranib</a>, <a href="http://en.wikipedia.org/wiki/Dasatinib" title="Dasatinib">Dasatinib</a>, <a href="http://en.wikipedia.org/wiki/Erlotinib" title="Erlotinib">Erlotinib</a>, <a href="http://en.wikipedia.org/wiki/Gefitinib" title="Gefitinib">Gefitinib</a>, <a href="http://en.wikipedia.org/wiki/Imatinib" title="Imatinib">Imatinib</a>, <a href="http://en.wikipedia.org/wiki/Lapatinib" title="Lapatinib">Lapatinib</a>, <a href="http://en.wikipedia.org/w/index.php?title=Lestaurtinib&amp;action=edit&amp;redlink=1" class="new" title="Lestaurtinib (page does not exist)">Lestaurtinib</a>, <a href="http://en.wikipedia.org/wiki/Nilotinib" title="Nilotinib">Nilotinib</a>, <a href="http://en.wikipedia.org/wiki/Sorafenib" title="Sorafenib">Sorafenib</a>, <a href="http://en.wikipedia.org/wiki/Sunitinib" title="Sunitinib">Sunitinib</a>, <a href="http://en.wikipedia.org/wiki/Vandetanib" title="Vandetanib">Vandetanib</a></td> </tr><tr> <th style="background: GreenYellow none repeat scroll 0% 50%; white-space: nowrap; -moz-background-clip: -moz-initial; -moz-background-origin: -moz-initial; -moz-background-inline-policy: -moz-initial; text-align: right;">Other</th> <td colspan="1" style="text-align: left; width: 100%; font-size: 95%;"><i><a href="http://en.wikipedia.org/wiki/Retinoid" title="Retinoid">retinoids</a></i> (<a href="http://en.wikipedia.org/wiki/Alitretinoin" title="Alitretinoin">Alitretinoin</a>, <a href="http://en.wikipedia.org/wiki/Tretinoin" title="Tretinoin">Tretinoin</a>) - <a href="http://en.wikipedia.org/wiki/Altretamine" title="Altretamine">Altretamine</a>, <a href="http://en.wikipedia.org/wiki/Amsacrine" title="Amsacrine">Amsacrine</a>, <a href="http://en.wikipedia.org/wiki/Anagrelide" title="Anagrelide">Anagrelide</a>, <a href="http://en.wikipedia.org/wiki/Arsenic_trioxide" title="Arsenic trioxide">Arsenic trioxide</a>, <a href="http://en.wikipedia.org/wiki/Asparaginase" title="Asparaginase">Asparaginase</a> (<a href="http://en.wikipedia.org/wiki/Pegaspargase" title="Pegaspargase">Pegaspargase</a>), <a href="http://en.wikipedia.org/wiki/Bexarotene" title="Bexarotene">Bexarotene</a>, <a href="http://en.wikipedia.org/wiki/Bortezomib" title="Bortezomib">Bortezomib</a>, <a href="http://en.wikipedia.org/wiki/Denileukin_diftitox" title="Denileukin diftitox">Denileukin diftitox</a>, <a href="http://en.wikipedia.org/wiki/Estramustine" title="Estramustine">Estramustine</a>, <a href="http://en.wikipedia.org/wiki/Ixabepilone" title="Ixabepilone">Ixabepilone</a>, <a href="http://en.wikipedia.org/wiki/Masoprocol" title="Masoprocol">Masoprocol</a>, <a href="http://en.wikipedia.org/wiki/Mitotane" title="Mitotane">Mitotane</a>, <a href="http://en.wikipedia.org/wiki/Testolactone" title="Testolactone">Testolactone</a></td></tr></tbody></table><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6598400160500789253-5987949976466239611?l=cell-wars.blogspot.com' alt='' /></div>writeowlnoreply@blogger.comtag:blogger.com,1999:blog-6598400160500789253.post-50573894420279664122008-04-02T17:28:00.000-07:002010-01-10T02:22:57.819-08:00<span style="color: rgb(204, 0, 0);"></span><span style="color: rgb(204, 0, 0);"> * Anti-sense oligonucleotide therapy</span><br /><span style="color: rgb(204, 0, 0);"> * AROMATASE INHIBITORS</span><br /><span style="color: rgb(204, 0, 0);"> * TGF-Beta Receptors</span><br /><span style="color: rgb(204, 0, 0);"> * Tumor Necrosis Factor-alpha Receptors</span><br /><span style="color: rgb(204, 0, 0);"> * NF-kB pathway</span><br /><span style="color: rgb(204, 0, 0);"> * Lymphotxin</span><br /><span style="color: rgb(204, 0, 0);"> * proteasome Inhibitor</span><br /><span style="color: rgb(204, 0, 0);"> * T-Cell Receptor for Antigen (TCR)</span><br /><span style="color: rgb(204, 0, 0);"> * Calcineurin</span><br /><span style="color: rgb(204, 0, 0);"> * FK506</span><br /><span style="color: rgb(204, 0, 0);"> * Cyclosporine</span><br /><span style="color: rgb(204, 0, 0);"> * Bortezomib</span><br /><span style="color: rgb(204, 0, 0);"> * monoclonal antibodies</span><br /><span style="color: rgb(204, 0, 0);"> * Infliximab</span><br /><span style="color: rgb(204, 0, 0);"> * Glucocorticoids</span><br /><span style="color: rgb(204, 0, 0);"> * SMAD proteins</span><br /><span style="color: rgb(204, 0, 0);"> * Calcium</span><br /><span style="color: rgb(204, 0, 0);"> * JAK-STAT pathways</span><br /><span style="color: rgb(204, 0, 0);"> * Receptor Tyrosine Kinases</span><br /><span style="color: rgb(204, 0, 0);"> * proto-oncogene</span><br /><span style="color: rgb(204, 0, 0);"> * PDGF</span><br /><span style="color: rgb(204, 0, 0);"> * EGF</span><br /><span style="color: rgb(204, 0, 0);"> * Trastuzumab</span><br /><span style="color: rgb(204, 0, 0);"> * Cetuximab</span><br /><span style="color: rgb(204, 0, 0);"> * RAF</span><br /><span style="color: rgb(204, 0, 0);"> * RAS</span><br /><span style="color: rgb(204, 0, 0);"> * Interferons</span><br /><span style="color: rgb(204, 0, 0);"> * IL-2</span><br /><span style="color: rgb(204, 0, 0);"> * IL-4</span><br /><span style="color: rgb(204, 0, 0);"> * Growth Hormone</span><br /><span style="color: rgb(204, 0, 0);"> * Leptin</span><br /><span style="color: rgb(204, 0, 0);"> * Prolactin</span><br /><span style="color: rgb(204, 0, 0);"> * Erythropoetin</span><br /><span style="color: rgb(204, 0, 0);"> * Thrombopoetin</span><br /><span style="color: rgb(204, 0, 0);"> * GM-CSF</span><br /><span style="color: rgb(204, 0, 0);"> * Cox Inhibitors</span><br /><span style="color: rgb(204, 0, 0);"> * Thiols</span><br /><span style="color: rgb(204, 0, 0);"> * Nitric Oxide</span><br /><span style="color: rgb(204, 0, 0);"> * MDR</span><br /><span style="color: rgb(204, 0, 0);"> * Antioxidants</span><br /><span style="color: rgb(204, 0, 0);"> * Bevacizumab</span><br /><span style="color: rgb(204, 0, 0);"> * Angiogenisis</span><br /><span style="color: rgb(204, 0, 0);"> * Oncolytic viruses</span><br /><span style="color: rgb(204, 0, 0);"> * Seneca ValleyVirus-001</span><br /><span style="color: rgb(204, 0, 0);"> * VEGF Trap (aflibercept)</span><br /><span style="color: rgb(204, 0, 0);"> * Herpes Simplex Virus NV1020</span><br /><span style="color: rgb(204, 0, 0);"> * Mullerian Inhibiting Substance</span><br /><span style="color: rgb(204, 0, 0);"> * B-Catenin</span><br /><span style="color: rgb(204, 0, 0);"> * APC tumor suppressor gene</span><br /><span style="color: rgb(204, 0, 0);"> * Wnt ligand</span><br /><span style="color: rgb(204, 0, 0);"> * Cytokine Receptors</span><br /><span style="color: rgb(204, 0, 0);"> * Signal Transduction</span><br /><span style="color: rgb(204, 0, 0);"> * v-sis</span><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6598400160500789253-5057389442027966412?l=cell-wars.blogspot.com' alt='' /></div>writeowlnoreply@blogger.comtag:blogger.com,1999:blog-6598400160500789253.post-29688639916644863862008-03-29T20:02:00.001-07:002008-03-29T20:04:05.364-07:00<a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://upload.wikimedia.org/wikipedia/commons/0/09/FluorescentCells.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 200px;" src="http://upload.wikimedia.org/wikipedia/commons/0/09/FluorescentCells.jpg" alt="" border="0" /></a>Endothelial cells under the microscope. Nuclei are stained blue with DAPI, microtubles are marked green by an antibody bound to FITC and actin filaments are labelled red with phalloidin bound to TRITC. Bovine pulmonary arthery endothelial cells<div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6598400160500789253-2968863991664486386?l=cell-wars.blogspot.com' alt='' /></div>writeowlnoreply@blogger.comtag:blogger.com,1999:blog-6598400160500789253.post-44717086000502003752008-03-29T09:19:00.000-07:002008-03-29T19:56:57.037-07:00<a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://upload.wikimedia.org/wikipedia/commons/f/f2/Neutrophil_with_anthrax_copy.jpg"><img style="margin: 0pt 10px 10px 0pt; float: left; cursor: pointer; width: 200px;" src="http://upload.wikimedia.org/wikipedia/commons/f/f2/Neutrophil_with_anthrax_copy.jpg" alt="" border="0" /></a><i>Neutrophil engulfing anthrax bacteria. Cover credit: The micrograph was taken by Volker Brinkmann with a Leo 1550 scanning electron microscope. Taken from PLoS Pathogens Vol. 1(3) November 2005</i><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6598400160500789253-4471708600050200375?l=cell-wars.blogspot.com' alt='' /></div>writeowlnoreply@blogger.comtag:blogger.com,1999:blog-6598400160500789253.post-66266884694342134602008-03-28T20:31:00.001-07:002008-03-28T20:31:38.625-07:00<a href="http://technorati.com/faves?sub=addfavbtn&amp;add=http://cell-wars.blogspot.com">Add to Technorati Favorites</a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6598400160500789253-6626688469434213460?l=cell-wars.blogspot.com' alt='' /></div>writeowlnoreply@blogger.comtag:blogger.com,1999:blog-6598400160500789253.post-85541752675033837732008-03-28T20:14:00.000-07:002008-03-28T20:19:56.338-07:00<span style="font-size:85%;"><a href="http://technorati.com/claim/wupgfj6s5p" rel="me">Technorati Profile</a></span><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6598400160500789253-8554175267503383773?l=cell-wars.blogspot.com' alt='' /></div>writeowlnoreply@blogger.comtag:blogger.com,1999:blog-6598400160500789253.post-5961776386558210882008-03-25T02:32:00.000-07:002008-03-25T02:34:37.082-07:00<a onblur="try {parent.deselectBloggerImageGracefully();} catch(e) {}" href="http://bp1.blogger.com/_erdqt4ZRIo0/R-i4-j71usI/AAAAAAAAACk/ooDSxcmYGdA/s1600-h/Resistance+Mechanisms.jpeg">This is a little outline I am working on to organize the resistance mechanisms of cancers and the techniques being tried to overcome this lethal characteristic. Please feel free to use it if you like, if you find it helpful. I will be updating it in the future.<br /></a><div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/6598400160500789253-596177638655821088?l=cell-wars.blogspot.com' alt='' /></div>writeowlnoreply@blogger.com