Wednesday, April 2, 2008


Drugs for chemotherapy generally fall into one of several categories. There are alkylating agents, anti-tumor antibiotics, Nitrosoureas, Antimetabolites, Topoisomerase Inhibitors, Mitotic Inhibitors, and Corticosteroid Hormones. This post concerns these more traditional treatments. Simply for background I will organize these drugs into their categories. This is taken from Wikipedia and provides a good overview of the current state of chemotherapy.

Double-click The terms in red for definitions

* Anti-sense oligonucleotide therapy
* TGF-Beta Receptors
* Tumor Necrosis Factor-alpha Receptors
* NF-kB pathway
* Lymphotxin
* proteasome Inhibitor
* T-Cell Receptor for Antigen (TCR)
* Calcineurin
* FK506
* Cyclosporine
* Bortezomib
* monoclonal antibodies
* Infliximab
* Glucocorticoids
* SMAD proteins
* Calcium
* JAK-STAT pathways
* Receptor Tyrosine Kinases
* proto-oncogene
* Trastuzumab
* Cetuximab
* Interferons
* IL-2
* IL-4
* Growth Hormone
* Leptin
* Prolactin
* Erythropoetin
* Thrombopoetin
* Cox Inhibitors
* Thiols
* Nitric Oxide
* Antioxidants
* Bevacizumab
* Angiogenisis
* Oncolytic viruses
* Seneca ValleyVirus-001
* VEGF Trap (aflibercept)
* Herpes Simplex Virus NV1020
* Mullerian Inhibiting Substance
* B-Catenin
* APC tumor suppressor gene
* Wnt ligand
* Cytokine Receptors
* Signal Transduction
* v-sis

Saturday, March 29, 2008

Endothelial cells under the microscope. Nuclei are stained blue with DAPI, microtubles are marked green by an antibody bound to FITC and actin filaments are labelled red with phalloidin bound to TRITC. Bovine pulmonary arthery endothelial cells

Neutrophil engulfing anthrax bacteria. Cover credit: The micrograph was taken by Volker Brinkmann with a Leo 1550 scanning electron microscope. Taken from PLoS Pathogens Vol. 1(3) November 2005

Friday, March 28, 2008

Add to Technorati Favorites

Technorati Profile

Apoptosis pathways

Apoptosis pathways

Double-click the list of technical words in red for instant definitions

Nature Reviews Cancer

Biology News Net - Gene Therapy

Biocompare Clinical Trials

Lookup in dictionary

Online Reference
Dictionary, Encyclopedia & more
Look in: Dictionary & thesaurus
Medical Dictionary
Legal Dictionary
Financial Dictionary
The news headlines shown above for Stem Cell Research are provided courtesy of Medical News Today.

MIT News: Cancer research

MIT News: Nanoscience and nanotechnology

MIT News: Biology, bioengineering and biotech

Medical News

Molecular Cancer Research current issue

Cell Metabolism

Cell Stem Cell

ecancermedicalscience News RSS Feed

ecancermedicalscience Articles RSS Feed

Chemotherapy News

JNCI Journal of the National Cancer Institute - recent issues

American Cancer Society :: News and Features

powered by
Today in History

Nature Signaling Update